1 – Scheme overview

Hemolysis, jaundice and lactescence of biological samples are the source of analytical interference . Most analyzers currently offer a possibility of quantifying serum indices allowing automated management of this interference. However, there is no standardization of these measures.

The aim of the proposed scheme is to help the laboratory to better control of the quality of index measurements by enabling it to assess its accuracy.

This scheme is suitable for all analyzers performing a measurement of serum indices (chemistry analyzers, hemostasis, serology, etc.).

INFORMATION: Two posters were presented during the 1st Francophone Days of Medical Biology, in September 2017, in Bordeaux:

• "EQA on hemolysis interference: results of a pilot survey" ==> Download the PDF (in french)
• "Measurement of serum indices: survey of laboratory practices" ==> Download the PDF (in french)

2 – Assessment frequency

Number of investigations per year : 4
Number of control samples per investigation: 2
Number of samples per year: 8

3 – List of analytes assessed

• Serum hemolysis index
• Serum jaundice index
• Serum lipemia index

4 – Description of the control samples

Lyophilized human control samples (to be resuspended in 1 mL of distilled water).