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Association for the Promotion of Quality Control in Medical Biology
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Sub-family: Haemostasis
2027 EQA PROGRAMMES
EQA 2027 - Circulating anticoagulants (ACC)
Expert Biologists - Programme Coordinators:
Béatrice GUILLEMIN
EQA performed since 2013
Number of analytical sites registered in 2026: 146
Programme organised by ProBioQual and placed under the aegis of the FAEEQ

1 – Programme overview

This External Quality Assessment programme evaluates the different techniques for detecting Lupus Anticoagulants. The main commercial reagents are represented.

Statistical reports are sent with supporting comments from the expert clinical biologists who coordinate the programme.

Participants are free to assay all analytes or only those they are interested in.

2 – Assessment frequency

Number of surveys per year: 4
Number of control samples per survey: 2
Number of samples per year: 8

3 – List of analytes assessed 

  • aPTT
  • Mixing test
  • Rosner index
  • Normalised sensitive/insensitive aPTT ratio
  • Dilute Russell's viper venom test (dRVVT screening and confirmation)
  • dRVVT screening and confirmation on mix
  • Staclot LA®
  • HemosIL Silica Clotting Time® (screening and confirmation)

The evaluation of test results is both quantitative and qualitative (negative, positive, equivocal).

4 – Description of the control samples

Lyophilised human control plasma (citrate) (samples to be resuspended in 1 mL of distilled water).

warning Sample volume: if necessary, order an additional kit.

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